Collaboration

Knock Out Mouse Project

The KOMP Repository is the official archive and distribution center for the Knockout Mouse Project (KOMP), a major 5-year trans-NIH initiative designed to generate null alleles in C57BL/6 embryonic stem (ES) cells for most genes not already available as knockout mice. Nearly 8500 genes are targeted for deletion, most in a conditional-ready format, by mutagenesis teams at “CSD” (Childrens Hospital of Oakland Research Institute, The Sanger Institute, and UC Davis) and at Regeneron, Inc. Here at the KOMP Repository at UC Davis and CHORI, you can obtain targeting vectors, ES cells, mice, and germplasm, as well as microinjection, genotyping, cryopreservation, breeding, and other services quickly and at reasonable cost to help you with your research project.

Interested? Want to know more? Read our blog, follow us on twitter, view our mobile app, or contact us directly.

Mutant Mouse Regional Resource Center

The MMRRC distributes and cryopreserves scientifically valuable, genetically engineered mouse strains and mouse ES cell lines with potential value for the genetics and biomedical research community. We are a national network of breeding and distribution facilities plus an information coordinating center serving together as NIH’s premier repository of spontaneous and induced mutant mouse and cell lines. The MMRRC is supported by the National Center for Research Resources at the National Institutes of Health.